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conclusions: (3)
"In 2 seasons with suboptimal antigenic match between vaccines and circulating strains, we could not demonstrate [vaccine effectiveness] in preventing influenza-related inpatient/[emergency department] or outpatient visits in children younger than 5 years. If they have to make that choice, what are they going to choose. Then, the protagonist demonstrates or tells how wonderful life is while on the drug.
You have to do x, y and z, but it's the faith as I've internalized it. Multiple studies have been done that have shown that if your study is funded by industry you are much likelier – about five times more likely – to come up with the result that's favorable to the drug company than if your study on the same subject is funded by an independent body unrelated to the company.
The workers in the industry aren't adding any real quality of life to anybody: imagine literally millions of doctors, pharmacists, pharmaceutical drug reps, and Big Pharma administrative staff sweating away at their jobs all day long, yet doing absolutely nothing to enhance the quality of life of the general public., Big Business has taken far too much control.
Ten or 100 people a year are dying because of the use of a particular drug or being hospitalized. Entrepreneurs are very, very important for productivity and growth in any national economy, and greed is in fact a powerful motivator for many. It should be pointed out that unambiguous evidence is hard to come by in this field, since doctors rarely confirm influenza with lab tests.
Influenza and vitamin D
The new influenza model
One of the unusual aspects of influenza outbreaks is their seasonality; in temperate climates winter is flu season.
I'm just a scientist doing my job and I have to leave the rest to God to protect me. The unspoken mores – what's the expected – is that you're going to approve as many of these drugs as you can.
This is the free market at work.
What I can say is that there are a number of other scientists within the FDA who have also worked with drugs that they know are not safe, even though the FDA has approved or allowed them to remain on the market. I was in a situation here with Vioxx where I was invited by Senator Grassley's office to testify. Where the FDA falls flat on its face is that there is a long period of time in which it does nothing.
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The FDA is responsible for 140,000 heart attacks and 60,000 dead Americans. Basically it's a tax. That paper pointed out that, even though the percentage of elderly getting an annual flu shot more than tripled from 1980 to 2001, there was no corresponding drop in the death rate.
Over-reliance on vaccinating the elderly, as the article from the Orthomolecular Medicine News Service puts it, also ignores another potent component of the host defenses a^ˆ" the innate immune system. When microbes like the influenza virus end up in the upper airways, they stimulate the production of an enzyme that converts 25(OH)D, the circulating inactive form of vitamin D, into the hormonally active 1,25(OH)2D (1,25-dihydroxyvitamin D).
What happens in the process is these patients are actually in a sense being denied a more effective treatment because the FDA doesn't require that drugs that come on to market be at least equivalent to, or better than, the drugs that are already there.
I think it's well established that depression is very common in adolescence.
From a very early age, I was taught the theories of free market economics. So the FDA is turning to desperate measures -- they're using 9/11 as a reason for banning the importation of drugs from Canada.
DR.” I ended the conversation by saying, “Well, industry may be your client, but it will never be my client. Clearly Vioxx was the problem. Then at the end the auctioneer gets on and says, “You know this drug could cause…,” and they rattle off 25 different things in three seconds. Where the FDA falls flat on its face is that there is a long period of time in which it does nothing. It should be pointed out that unambiguous evidence is hard to come by in this field, since doctors rarely confirm influenza with lab tests. Institute of Medicine: 200 IU/day from birth to age 50, 400 IU/day fom 50 to 70, and 600 IU/day for anyone over 70.
The editor of The Lancet also realized that what the high level FDA officials were saying to him was a pack of lies.